Thursday, June 25, 2026

Bitget Launches Stock+, Bringing Real US Stocks to Crypto-Native Investors

 

VICTORIA, Seychelles - Tuesday, 23. June 2026

(GLOBE NEWSWIRE) -- Bitget, the world’s largest Universal Exchange (UEX), has launched Stock+, a new feature under its Stocks 2.0 ecosystem that enables users to purchase real US stocks directly using USDC and other digital assets. The launch marks another step toward a future where crypto and traditional financial markets operate within the same account, allowing users to move between digital assets and equities without the fragmentation that has historically separated the two worlds.

For decades, access to US equities has depended on local brokers, bank transfers, account approvals, and jurisdiction-specific infrastructure. Stock+ introduces a different model. Users can fund their accounts with digital assets, convert them into USDC, and gain exposure to publicly listed companies through a streamlined, crypto-native experience. The result is a trading environment where global markets become increasingly accessible fr0m a single platform.

Unlike synthetic products or derivatives, Stock+ provides ownership of underlying shares executed through regulated brokers. Users are eligible for cash dividends and stock split adjustments associated with their holdings, while trading hours remain synchronized with US pre-market, regular market, and after-hours sessions.

"Bitget was among the first exchanges to bring together crypto, tokenized assets, commodities, and equities under the Universal Exchange vision. Stock+ is the next evolution of that strategy," said Gracy Chen, CEO of Bitget. "Access is important, but ownership matters too. Giving users access to real ownership of US-listed companies is how we actually bridge financial markets. The platforms that succeed will be the ones that combine access, ownership, and flexibility in a single experience."

Stock+ also supports inbound stock transfers fr0m participating brokers through standard transfer processes, allowing users to consolidate existing US equity holdings within a unified portfolio environment. Combined with crypto-funded purchasing, the feature expands the ways investors can access and manage traditional financial assets through Bitget.

With Stock+, Bitget adds direct ownership of US-listed equities to its growing suite of stock market products, further advancing its vision of a Universal Exchange where crypto and traditional financial markets coexist within a single platform.

In early June 2026, Bitget announced a major 2.0 upgrade to its stock-related services, kicking off with the launch of Reality, a regulated RWA protocol, and its issued tokenized stocks (rToken). To date, Bitget has listed over 500 leading US stocks and ETFs, including SpaceX, Tesla, and NVIDIA, with the Assets Under Management (AUM) of rToken exceeding $50 million. The introduction of Stock+ marks another pivotal step in the Bitget Stocks 2.0 evolution, offering users accustomed to traditional brokerage experiences a more seamless and intuitive interface for transfers and trading.

To celebrate the launch, Stock+ trading fees start fr0m 0.1%, with a 50% promotional discount available through August 31, 2026.

To find out more, visit here.

About Bitget

Bitget is the world's largest Universal Exchange (UEX), serving over 125 million users and offering access to over 2M crypto tokens, 100+ tokenized stocks, ETFs, commodities, FX, and precious metals such as gold. The ecosystem is committed to helping users trade smarter with its AI agent, which co-pilots trade execution. Bitget is driving crypto adoption through strategic partnerships with LALIGA and MotoGP™. Aligned with its global impact strategy, Bitget has joined hands with UNICEF to support blockchain education for 1.1 million people by 2027. Bitget currently leads in the tokenized TradFi market, providing the industry's lowest fees and highest liquidity across 150 regions worldwide.

For more information, visit: Website | Twitter | Telegram | LinkedIn | Discord

Risk Warning: Digital asset prices are subject to fluctuation and may experience significant volatility. Investors are advised to only allocate funds they can afford to lose. The value of any investment may be impacted, and there is a possibility that financial objectives may not be met, nor the principal investment recovered. Independent financial advice should always be sought, and personal financial experience and standing carefully considered. Past performance is not a reliable indicator of future results. Bitget accepts no liability for any potential losses incurred. Nothing contained herein should be construed as financial advice. For further information, please refer to our Terms of Use.

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/c9f7aec7-459d-4588-a541-ad7cafab4389

Contacts :

For media inquiries, please contact: media@bitget.com

PUMA Dominates HYROX World Championships From Elite Athlete Performances to Community Initiatives

 (BUSINESS WIRE) -- Global sports brand PUMA continued its HYROX dominance at the 2026 HYROX World Championships with a host of standout elite athlete performances and iconic community moments.


Leading the charge was Jess Pettrow, who won the Mixed Relay with Australia for the second year in a row, with the team defending their title with an epic time of 50:19. Pettrow’s golden moment followed a fourth place finish with partner Joanna Wietrzyk in the Women’s Elite 15 Doubles, making it a highly successful weekend for the PUMA athlete.


In addition to her strong showing in the Women’s Elite Doubles, Australian athlete Wietrzyk also secured a magnificent second place in the Women’s Elite 15 Solo race - a positive way to finish a remarkable season in which she broke the World Record twice and took a clean sweep of the HYROX Majors.


Elsewhere there were also second place finishes for Great Britain’s Lucy Procter in the Women’s Elite15 Doubles, Linda Meier in the Mixed Relay for team Germany, and the transatlantic duo of Jake Williamson and Hunter McIntyre in the Men’s Elite15 Doubles. PUMA had a further five podium finishes across the various age group categories in this year’s HYROX World Championships.


Across the weekend, PUMA athletes consistently delivered on the biggest stage, showcasing the speed, endurance and strength required to compete at the pinnacle of the sport.


Competing in the PUMA Deviate Elite HYROX, the first-of-its-kind performance shoe specifically engineered for HYROX racing, PUMA athletes once again demonstrated the performance advantages of footwear designed for the unique demands of hybrid competition.


Alongside the racing action, PUMA maintained a significant presence throughout the HYROX World Championships, bringing its highly anticipated NITRO™ Lab experience to Stockholm with more than 100 pairs of Deviate Elite HYROX won by the community. In addition, more than 500 people participated in the week’s biggest shake out run that ended at the famous Grona Lund theme park, reinforcing PUMA's position as a leading force within the HYROX community.


The results continue a landmark year for PUMA in HYROX, following multiple world records, Major victories and continued innovation through its dedicated HYROX footwear and athlete programmes.


The new colourway of PUMA’s Deviate Elite HYROX will be available globally 1st July on PUMA.com, in PUMA flagship stores, at HYROX events, on HYROX World, and at selected retailers across North America, Europe, Latin America, Asia and Australia.


For more information visit www.puma.com and follow @pumatraining, or visit www.hyrox.com and follow @hyroxworld.


NITRO™ Lab & Shakeout Run Imagery: Download Here


HYROX Elite15 Athlete Imagery: Download Here


PUMA


PUMA is one of the world’s leading sports brands, designing, developing, and selling footwear, apparel and accessories. Founded in 1948, PUMA helps the world’s best athletes and teams perform at their best with its innovative products. Known for its iconic cat logo and the Formstrip, the company offers performance products in categories such as Football, Running and Training. Its Sportstyle collections are rooted in sports and inspire consumers by celebrating sports culture. With its long history and strong heritage, PUMA is proud of having one of the strongest archives in the industry, with many iconic products such as the Suede and the Speedcat. The PUMA Group owns the brands PUMA, Cobra Golf and stichd. The company distributes its products in over 120 countries, employs more than 20,000 people and is headquartered in Herzogenaurach/Germany. For more information, please visit https://about.puma.com.


 


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Contacts

Media Contact: Stefan.Popovic@puma.com / Sarah.Fuller@puma.com


 

Rockstar Games Announces Pre-Orders for Grand Theft Auto VI

 (BUSINESS WIRE) -- Rockstar Games®, a publishing label of Take-Two Interactive Software, Inc. (NASDAQ: TTWO), is excited to announce that pre-orders for Grand Theft Auto VI will begin on June 25, 2026, at midnight local time.


Launching November 19, 2026, for the PlayStation® 5 computer entertainment systems and Xbox Series X|S games and entertainment systems for $79.99, Grand Theft Auto VI features a single-player experience set in the biggest, most immersive evolution of the series yet.


The Grand Theft Auto VI: Ultimate Edition amplifies this experience with an exclusive collection of premium vehicles, weapons, apparel, and action threaded across all aspects of Jason and Lucia’s story, and will be available for $99.99.


All Grand Theft Auto VI pre-orders and purchases before November 20, 2026, will include the Vintage Vice City Pack, a collection of items that flash back to when the neon burned brightest, alongside a free month of GTA+ for digital pre-orders, which will be the best way to get the most out of the ever-evolving world of GTA Online and instantly redeemable so that players can jump into Grand Theft Auto V and other classic Rockstar titles as part of the GTA+ Games Library.


Players who pre-order digital versions of Grand Theft Auto VI will be able to begin pre-loading on November 12, 2026 to ensure they are able to play at launch on November 19, 2026. The physical version of Grand Theft Auto VI, containing a download code inside the box, will be available starting November 12, 2026 to support pre-loading.


Grand Theft Auto VI will be available at the PlayStation® Store, Microsoft Store, Rockstar Games Store, and global retailers and storefronts.


Grand Theft Auto VI is not yet rated. Further details can be found at www.rockstargames.com/VI.


About Grand Theft Auto VI


Vice City, USA. Jason and Lucia have always known the deck is stacked against them. But when an easy score goes wrong, they find themselves on the darkest side of the sunniest place in America, in the middle of a conspiracy stretching across the state of Leonida — forced to rely on each other more than ever if they want to make it out alive.


About Rockstar Games


Rockstar Games cemented their reputation as creators of complex living worlds with the Grand Theft Auto series, one of the most successful entertainment properties of all time with over 470 million units sold-in worldwide. Through a string of critically acclaimed games including the Grand Theft Auto series, the Red Dead Redemption series, the Max Payne series, Bully, L.A. Noire, the Midnight Club series, and The Warriors, Rockstar Games has helped propel interactive entertainment into the center of modern culture. Follow Rockstar Games on X, Instagram, YouTube, Facebook, Twitch, Discord, WhatsApp, and TikTok.


About Take-Two Interactive Software


Headquartered in New York City, Take-Two Interactive Software, Inc. is a leading developer, publisher, and marketer of interactive entertainment for consumers around the globe. We develop and publish products principally through Rockstar Games, 2K, and Zynga. Our strategy is to create hit entertainment experiences, delivered on every platform relevant to our audience through a variety of sound business models. Our pillars - creativity, innovation, and efficiency - guide us as we strive to create the highest quality, most captivating experiences for our consumers. The Company’s common stock is publicly traded on NASDAQ under the symbol TTWO. For more corporate and product information please visit our website at http://www.take2games.com.


All trademarks and copyrights contained herein are the property of their respective holders.


Cautionary Note Regarding Forward-Looking Statements


The statements contained herein, which are not historical facts, including statements relating to Take-Two Interactive Software, Inc.'s ("Take-Two," the "Company," "we," "us," or similar pronouns) outlook, are considered forward-looking statements under federal securities laws and may be identified by words such as "anticipates," "believes," "estimates," "expects," "intends," "plans," "potential," "predicts," "projects," "seeks," "should," "will," or words of similar meaning and include, but are not limited to, statements regarding the outlook for our future business and financial performance. Such forward-looking statements are based on the current beliefs of our management as well as assumptions made by and information currently available to them, which are subject to inherent uncertainties, risks, and changes in circumstances that are difficult to predict. Actual outcomes and results may vary materially from these forward-looking statements based on a variety of risks and uncertainties, including risks relating to the timely release and significant market acceptance of our games; the risks of conducting business internationally, including as a result of unforeseen geopolitical events; the impact of changes in interest rates by the Federal Reserve and other central banks, including on our short-term investment portfolio; the impact of inflation; volatility in foreign currency exchange rates; our dependence on key management and product development personnel; our dependence on our NBA 2K and Grand Theft Auto products and our ability to develop other hit titles; our ability to leverage opportunities on PlayStation®5 and Xbox Series X|S; factors affecting our mobile business, such as player acquisition costs; and the ability to maintain acceptable pricing levels on our games.


Other important factors and information are contained in the Company's most recent Annual Report on Form 10-K, including the risks summarized in the section entitled "Risk Factors," the Company’s most recent Quarterly Report on Form 10-Q, and the Company's other periodic filings with the SEC, which can be accessed at www.take2games.com. All forward-looking statements are qualified by these cautionary statements and apply only as of the date they are made. The Company undertakes no obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise.


 


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Contacts

Carey Waggoner

Rockstar Games

(212) 334-6633

Carey.Waggoner@rockstargames.com


Alan Lewis (Corporate Press)

Take-Two Interactive Software, Inc.

(646) 536-2983

Alan.Lewis@take2games.com


 

NTT DATA and Cursor Partner to Accelerate Enterprise-Grade Modernization and AI Governance

  LONDON - Wednesday, 24. June 2026 AETOSWire  



NTT DATA leveraging Cursor to strengthen its own engineering and delivery model.

Enterprise-grade governance helps modernize and transform delivery with greater trust and control.

 


(BUSINESS WIRE)--NTT DATA, a global leader in AI, digital business and technology services, today announced a strategic partnership with Cursor, the leading multi-model AI coding platform. Under this initiative, NTT DATA will use Cursor’s advanced AI agents to power the innovation of its global software engineering and delivery models. Cursor will enable NTT DATA to design, build and modernize enterprise systems with greater speed and control, while supporting the governance enterprises require.


The collaboration marks a strategic advancement in NTT DATA’s transformation into an AI-native services company, enhancing how the company designs, builds and modernizes mission-critical systems. NTT DATA is operationalizing AI inside its engineering and delivery engine with enterprise-grade controls to enable faster modernization of clients’ legacy estates, accelerate cloud and AI transformation initiatives, and drive greater consistency across delivery environments.


Including AI agents directly in the engineering layer helps ensure that application modernization and development efforts remain aligned with enterprise-wide AI strategies. These capabilities enhance NTT DATA’s broader full-stack portfolio.


“Enterprise modernization is no longer just about moving systems to the cloud—it is about reimagining how software is built and operated in the age of AI,” said Abhijit Dubey, CEO and Chief AI Officer, NTT DATA, Inc. "Through our partnership with Cursor, we will use AI in the core of our engineering and delivery model, enabling us to modernize faster, improve consistency at scale and deliver greater value to clients. By applying these capabilities inside our own business first, we can help organizations adopt AI with greater confidence, governance and measurable impact.”


Cursor is the leading multi-model AI coding platform, embedding advanced AI agents directly into developers’ environments to write, review, refactor and modernize code with codebase-wide context across leading models. For NTT DATA, this brings AI-native acceleration into the core of its global engineering and delivery model, paired with enterprise-grade governance, including organization-wide privacy mode, Single Sign-On, centralized administration, granular agent controls, and audit-ready policy enforcement so modernization happens faster, with greater consistency, trust and control. For joint clients, NTT DATA’s use of Cursor turns into real-world results, guiding enterprises through secure scalable, and responsible AI adoption and accelerating the modernization of legacy code bases and AI transformation while keeping delivery aligned with enterprise-wide AI strategies.


“NTT DATA is putting AI at the core of how engineers modernize complex systems,” said Jordan Topoleski, Chief Operating Officer, Cursor. “By pairing Cursor agents with enterprise-grade governance and structured enablement, NTT DATA is proving how AI changes the way software gets built and delivered at global scale, and we are proud to support their teams as they bring it to enterprises worldwide.”


NTT DATA is initially deploying Cursor Enterprise to priority engineering teams and will expand deployments as adoption scales globally. The company also plans to establish a Cursor Center of Excellence to help scale these capabilities across global practices and industries.


To learn more about NTT DATA, visit our website.


About NTT DATA


NTT DATA is a $30+ billion business and technology services leader, serving 75% of the Fortune Global 100. We are committed to accelerating client success and positively impacting society through responsible innovation. We are one of the world’s leading AI and digital infrastructure providers, with unmatched capabilities in enterprise-scale AI, cloud, security, connectivity, data centers and application services. Our consulting and industry solutions help organizations and society move confidently and sustainably into the digital future. As a Global Top Employer, we have experts in more than 70 countries. We also offer clients access to a robust ecosystem of innovation centers as well as established and start-up partners. NTT DATA is part of NTT Group, which invests over $3 billion each year in R&D.


Visit us at nttdata.com.


About Cursor


Cursor is the best way to build software with AI. Helping teams solve the hardest problems, Cursor builds an ecosystem of tools to write, review, and maintain code more efficiently and intelligently. Serving the majority of the Fortune 500 and tens of thousands of engineering teams globally, Cursor is accelerating the future of software development with enterprise-grade AI-assisted coding capabilities. Learn more at https://cursor.com/


 


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Contacts

 

Media Contact

NTT DATA, Inc.

Dan.Smith@nttdata.com

Wednesday, June 24, 2026

Takeda Announces New Assignments of Directors and Appointment of Julie Kim as Representative Director, President and CEO


 OSAKA, Japan & CAMBRIDGE, Mass. - 

Board of Directors appoints Julie Kim as Representative Director, President & CEO following shareholder vote

Announces new appointments and assignments of directors

 


(BUSINESS WIRE) -- In the final step of its 18-month CEO transition, Takeda (TOKYO:4502/NYSE:TAK) today announced that Julie Kim was officially appointed Takeda’s Representative Director, President and Chief Executive Officer.


During the 150th Annual General Meeting of Shareholders, which took place in Osaka, Japan, shareholders elected Julie as a new internal director to the Board of Directors. Following the vote and conclusion of the meeting, the Board of Directors appointed her as Representative Director, President & CEO. Upon conclusion of the meeting, former president & CEO Christophe Weber retired from the Company and the Board.


Chair of the Board of Directors Meeting, Masami Iijima, commented: “On behalf of Takeda’s Board of Directors, I would like to congratulate Julie Kim on becoming Takeda’s President and CEO. The Board of Directors is confident in Ms. Kim to drive executional excellence as Takeda launches a number of highly anticipated medicines and grows long-term shareholder value. The Board would like to thank Christophe Weber for his 12 years of extraordinary service to Takeda. He delivered global scale and an innovative pipeline, while strengthening Takeda’s reputation globally as a company built on integrity. We wish him all the best in the future.”


President & CEO, Julie Kim, commented: “It is a privilege and honor to lead Takeda and position the company for long-term profitable growth and increased patient impact. I would like to thank Christophe for his leadership over the last 12 years and in particular, his guidance during the transition period. I would also like to thank our shareholders, Mr. Iijima and the Board of Directors, including the six retiring external Directors, for their support. Going forward, I’m excited to partner with the elected Board to continue our important work for patients and other stakeholders. As we enter our next era, we have three major launches planned in the next 12 months and we are continuing to advance our robust pipeline of five additional highly innovative late-stage assets. Our growth roadmap built around our two strategic horizons positions us for a successful future for patients, our talented employees and shareholders.”


Julie Kim brings more than three decades of global healthcare experience and a track record of advancing innovation, expanding access to life-changing medicines and delivering meaningful impact for patients and communities. She joined Takeda in 2019 through the acquisition of Shire and held several executive-level roles, including president of the Plasma-Derived Therapies Business Unit and president of the U.S. Business Unit before becoming CEO-elect in 2025. Learn more about Julie’s experience and leadership roles on Takeda.com.


To help guide Takeda’s next growth chapter, shareholders elected members of the Board of Directors, including three new external directors: Bruce Broussard, Koichiro Kimura and Dr. Paul Stoffels.


Mr. Broussard brings decades of leadership experience with large global companies and international business management, and deep expertise in the U.S. healthcare system.


As the former Chairman of PricewaterhouseCoopers in Japan, Mr. Kimura has extensive experience in geopolitical risk and corporate governance across the Asia-Pacific region.


Dr. Stoffels brings an exceptional track record in pharmaceutical R&D innovation, having overseen the global launch of 25 medicines, first as Chief Science Officer at Johnson & Johnson, and then as CEO of biotechnology company Galapagos.


At the Board of Directors and the Audit and Supervisory Committee meetings following the Annual Meeting of Shareholders, new assignments of directors were determined. Takeda's Board of Directors has eight members serving as external directors out of a total of 11 members, helping to ensure transparency and objectivity. An external director will continue to chair the Board of Directors meeting. The Audit and Supervisory Committee, the Nomination Committee and the Compensation Committee will be composed solely of external directors including their chairs.


1.

New Assignment of Directors Who Are Not Audit and Supervisory Committee Members

(Effective June 24, 2026)


Name


Category


Role


Julie Kim

Internal/New


Representative Director, President & Chief Executive Officer


Milano Furuta

Internal/Existing


Director, Chief Financial Officer


Andrew Plump

Internal/Existing


Director, President, Research & Development


Masami Iijima

External/Existing


External Director, Chair of the Board Meeting


Steven Gillis

External/Existing


External Director


John Maragnore

External/Existing


External Director


Paul Stoffels*

External/New


External Director


Miki Tsusaka

External/Existing


External Director


*Dr. Paul Stoffels is also a Substitute Audit and Supervisory Committee member

2.

Directors Who Are Audit and Supervisory Committee Members (Effective June 24, 2026)


Name


Category


Role


Koichiro Kimura

External/New


External Director, Head of Audit and Supervisory Committee


Bruce Broussard

External/New


External Director, Audit and Supervisory Committee Member


Kimberly A. Reed

External/Existing


External Director, Audit and Supervisory Committee Member


3.


New Assignment of Nomination Committee and Compensation Committee Members

(Effective June 24, 2026)


 

Nomination committee:


 

Masami Iijima (Chairperson), Steven Gillis and Koichiro Kimura


 

(Observer: Julie Kim)


 

Compensation committee:


 

John Maraganore (Chairperson), Masami Iijima, Kimberly A. Reed, Miki Tsusaka


About Takeda

Takeda is focused on creating better health for people and a brighter future for the world. We aim to discover and deliver life-transforming treatments in our core therapeutic and business areas, including gastrointestinal and inflammation, rare diseases, plasma-derived therapies, oncology, neuroscience and vaccines. Together with our partners, we aim to improve the patient experience and advance a new frontier of treatment options through our dynamic and diverse pipeline. As a leading values-based, R&D-driven biopharmaceutical company headquartered in Japan, we are guided by our commitment to patients, our people and the planet. Our employees in approximately 80 countries and regions are driven by our purpose and are grounded in the values that have defined us for more than two centuries. For more information, visit www.takeda.com.


Important Notice

For the purposes of this notice, “press release” means this document, any oral presentation, any question and answer session and any written or oral material discussed or distributed by Takeda Pharmaceutical Company Limited (“Takeda”) regarding this press release. This press release (including any oral briefing and any question-and-answer in connection with it) is not intended to, and does not constitute, represent or form part of any offer, invitation or solicitation of any offer to purchase, otherwise acquire, subscribe for, exchange, sell or otherwise dispose of, any securities or the solicitation of any vote or approval in any jurisdiction. No shares or other securities are being offered to the public by means of this press release. No offering of securities shall be made in the United States except pursuant to registration under the U.S. Securities Act of 1933, as amended, or an exemption therefrom. This press release is being given (together with any further information which may be provided to the recipient) on the condition that it is for use by the recipient for information purposes only (and not for the evaluation of any investment, acquisition, disposal or any other transaction). Any failure to comply with these restrictions may constitute a violation of applicable securities laws.


The companies in which Takeda directly and indirectly owns investments are separate entities. In this press release, “Takeda” is sometimes used for convenience where references are made to Takeda and its subsidiaries in general. Likewise, the words “we”, “us” and “our” are also used to refer to subsidiaries in general or to those who work for them. These expressions are also used where no useful purpose is served by identifying the particular company or companies.


The product names appearing in this document are trademarks or registered trademarks owned by Takeda, or their respective owners.


Forward-Looking Statements

This press release and any materials distributed in connection with this press release may contain forward-looking statements, beliefs or opinions regarding Takeda’s future business, future position and results of operations, including estimates, forecasts, targets and plans for Takeda. Without limitation, forward-looking statements often include words such as “targets”, “plans”, “believes”, “hopes”, “continues”, “expects”, “aims”, “intends”, “ensures”, “will”, “may”, “should”, “would”, “could”, “anticipates”, “estimates”, “projects”, “forecasts”, “outlook” or similar expressions or the negative thereof. These forward-looking statements are based on assumptions about many important factors, including the following, which could cause actual results to differ materially from those expressed or implied by the forward-looking statements: the economic circumstances surrounding Takeda’s global business, including general economic conditions in Japan and the United States and with respect to international trade relations; competitive pressures and developments; changes to applicable laws and regulations, including drug pricing, tax, tariff and other trade-related rules; challenges inherent in new product development, including uncertainty of clinical success and decisions of regulatory authorities and the timing thereof; uncertainty of commercial success for new and existing products; manufacturing difficulties or delays; fluctuations in interest and currency exchange rates; claims or concerns regarding the safety or efficacy of marketed products or product candidates; the impact of health crises, like the novel coronavirus pandemic; the success of our environmental sustainability efforts, in enabling us to reduce our greenhouse gas emissions or meet our other environmental goals; the extent to which our efforts to increase efficiency, productivity or cost-savings, such as the integration of digital technologies, including artificial intelligence, in our business or other initiatives to restructure our operations will lead to the expected benefits; and other factors identified in Takeda’s most recent Annual Report on Form 20-F and Takeda’s other reports filed with the U.S. Securities and Exchange Commission, available on Takeda’s website at: https://www.takeda.com/investors/sec-filings-and-security-reports/ or at www.sec.gov. Takeda does not undertake to update any of the forward-looking statements contained in this press release or any other forward-looking statements it may make, except as required by law or stock exchange rule. Past performance is not an indicator of future results and the results or statements of Takeda in this press release may not be indicative of, and are not an estimate, forecast, guarantee or projection of Takeda’s future results.


 


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Contacts

Investor Relations

Christopher O’Reilly

Takeda.ir.contact@takeda.com


Media Relations

Tsuyoshi Tada (Tokyo)

toiawase_kouhou@takeda.co.jp

Kristi Bond (Boston)

Media_relations@takeda.com

Tigo Energy Predict+ Forecasting Platform Helps YASNO Keep Energy Flowing in Ukraine

 Advanced energy prediction platform, Predict+, enables Ukrainian utility to better maintain grid service through demand surges, highly variable weather, and infrastructure disruptions.


LOS GATOS, Calif. & KYIV, Ukraine--(BUSINESS WIRE)--Tigo Energy, Inc. (NASDAQ: TYGO) (“Tigo” or “Company”), a leading provider of intelligent solar and energy software solutions, today announced that Ukrainian electric utility, YASNO, is the latest enterprise-tier customer to deploy the Tigo Predict+ platform. The AI Energy platform empowers utility operators to adapt to real-world demand challenges as they balance renewable and baseload generation sources. Predict+ currently manages more than 650 GWh and delivers 97.5% forecast accuracy for utility customers.


As the leading provider of electricity, gas, and energy-efficiency solutions in Ukraine, YASNO serves more than 2.5 million households in the Kyiv, Dnipropetrovsk, and Donetsk regions, as well as more than 64,000 business customers. YASNO uses the Predict+ platform in ways that go far beyond typical utility use cases, leveraging Tigo neural network-based AI to maintain grid stability amid highly variable weather and unpredictable infrastructure damage. The roll-out of Predict+ by YASNO followed the successful conclusion of a configuration and testing pilot phase in the Dnipropetrovsk region, one of the most challenging regions for forecasting due to its diverse customer base and highly variable weather conditions. Preparations for the broader deployment of Predict+ are underway, including system configuration and integrating historical data across other YASNO companies to support the future rollout of forecasting capabilities.


“The broader implementation of this platform will continue to improve the accuracy of our hourly electricity demand forecasts and reduce imbalance settlement costs. This means better planning, more efficient resource utilization, and an even more reliable service for our customers,” said Olena Senkina, Head of Electricity Department at YASNO.


With smart meter integration, Predict+ models each meter individually and performs extensive calculations on actual, historical, and average data to closely predict usage patterns. Even without smart meters, Predict+ produces highly accurate predictions about energy demand. The platform’s functional domains include market insights, customer insights, profit analysis, regulatory support, and real-time integration of energy spot market pricing. Predict+ analyzes multiple data sources simultaneously to determine how much electricity will likely be consumed or generated during each hour of the day. The data sources include weather forecasts from multiple providers, current weather conditions across regions, historical hourly customer consumption and generation data, and operational data from previous days. Based on this extensive dataset, Predict+ generates multiple forecast scenarios that are continuously updated. As weather conditions, including temperature, wind speed, and solar irradiation levels, change, Predict+ adjusts calculations, analyzes deviations from previous forecasts, and continuously improves the accuracy of future predictions.


“Many of the baseline parameters we use in Predict+ originate from relatively normal grid operations, but for the YASNO team, we had to quickly add data and variables that included disruptions for core grid elements,” said Archie Roboostoff, vice president of software at Tigo. “The Predict+ neural network and data framework allows us to rapidly ingest large amounts of new information, live data streams, and historical data, including things like insults to grid infrastructure, and refactor such that the future becomes vastly more predictable. That is the real power of Predict+, and with YASNO, those capabilities have once again been validated.”


Predict+ is available for utilities, energy retailers, energy traders, independent power producers, large commercial & industrial customers, and more in the US and Europe. For more information, please visit the Predict+ website, and for a personalized overview of the platform, schedule a demo here.


About Tigo Energy


Founded in 2007, Tigo Energy, Inc. (Nasdaq: TYGO) is a worldwide leader in the development and provider of smart hardware and software solutions that enhance safety, increase energy yield, and lower operating costs of residential, commercial, and utility-scale solar systems. Tigo combines its Flex MLPE (Module Level Power Electronics) and solar optimizer technology with intelligent, cloud-based software capabilities for advanced energy monitoring and control. Tigo MLPE products maximize performance, enable real-time energy monitoring, and provide code-required rapid shutdown at the module level. The company also develops and manufactures products such as inverters and battery storage systems for the residential solar-plus-storage market. For more information, please visit www.tigoenergy.com.


About YASNO


YASNO is one of Ukraine’s leading energy brands, bringing together companies that provide electricity and natural gas supply, energy efficiency solutions, and electric mobility services. YASNO serves more than 2.5 million households in Kyiv, Dnipropetrovsk, and Donetsk regions, as well as over 64,000 business customers across Ukraine. YASNO’s ecosystem of products—including solar power plants (PV systems), battery energy storage systems (BESS), and energy management solutions—helps businesses reduce costs, improve energy efficiency, and strengthen energy resilience. The company is committed to delivering high-quality customer service and continuously expanding its digital service capabilities.


 


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Contacts

 

Technica Communications

Luis de Leon

Email: tigoenergy@technica.inc


 

Thales Secures Significant U.S. Army LOCODA Radio Order Following Rapid Development Push

 The U.S. Army has selected the Thales Radio Adaptable Transport (RAT) to support the Service’s Low Cost Data Architecture (LOCODA) tactical communications transformation effort.

Rapidly developed and production ready, LOCODA RAT delivers scalable, modular, multi-transport voice and data connectivity designed to support evolving operational requirements across current and future mounted platforms.

Built on a commercial-off-the-shelf and non-developmental item approach, LOCODA RAT scales production, supports continuous upgrades, and reduces integration complexity and lifecycle costs.

 


(BUSINESS WIRE) -- Delivering capability at mission speed, Thales subsidiary, Thales Defense & Security, Inc. (TDSI), has secured an order for up to 5,000 Low Cost Data Architecture (LOCODA) Radio Adaptable Transport (RAT) platforms. The Thales RAT solution, which was conceived, developed and field-ready less than four months, modernizes voice and data communications and integrates effortlessly into radio mounts across all current and future U.S. Army vehicle platforms.


The LOCODA RAT platform provides soldiers with a reliable, adaptable communications capability they can depend on across any mission and environment. By reusing existing vehicle radio mounts and supporting a wide range of radios and mission modules, it reduces setup time and simplifies integration in the field. Soldiers gain secure, flexible voice and data connectivity that scales with their needs, with a system that can be quickly updated to keep pace with evolving threats and mission demands.


“The Army doesn’t have time to wait for capability, and with the Thales LOCODA RAT solution, they didn’t have to,” said Gary Kidwell, Vice President of Communications Systems, TDSI. “In less than four months, we moved from concept to field-ready, providing a reliable, adaptable communications capability. This is about giving warfighters immediate access to secure, flexible voice and data connectivity that can adapt as quickly as the missions and the threat.”


Designed using a COTS and NDI approach, LOCODA RAT enables scalable production and continuous capability growth while reducing integration complexity and lifecycle costs.


Supporting single-channel, multi-channel, and multi-transport operational modes, the Thales LOCODA RAT is designed with standardized vehicle and radio interfaces for power, GPS, audio, and data connectivity. Additional capabilities include third-party system integration, intercom functionality, multi-vendor compatibility across TSM radios and AES-256 encryption security.


Utilizing the TrellisWare (TSM™) MANET waveform, LOCODA RAT provides the security of Sensitive But Unclassified – Encrypted (SBU-E) voice and data communications while supporting both wideband and narrowband radio waveforms. Its modular architecture enables simultaneous embedding of additional radios, amplifiers, and mission modules to extend communication range and expand transport options.


This order supports the Army’s broader effort to modernize tactical communications infrastructure with agile, mission-adaptable solutions capable of supporting distributed operations across increasingly contested environments.


About Thales


Thales (Euronext Paris: HO) is a global leader in advanced technologies for the Defence, Aerospace, and Cyber & Digital sectors. Its portfolio of innovative products and services helps address several major challenges: sovereignty, security, sustainability and inclusion.


 


The Group allocates €4.5 billion per year in Research & Development in key areas, particularly for critical environments, such as Artificial Intelligence, Cybersecurity, Quantum and Cloud technologies. Thales has more than 85,000 employees in 65 countries. In 2025, the Group generated sales of €22.1 billion.


 


Recent images of Thales and its Defense, Aerospace and Cyber & Digital activities can be found on the Thales Media Library (https://medialibrary.thalesgroup.com/portals/uotw97dr/THALESMediaLibrary). For any specific requests, please contact the Media Relations team.


 


About Thales in the U.S.


For more than a century, Thales has delivered proven, trusted and secure solutions to customers across the United States. The company brings a strong national footprint and a deeply skilled workforce dedicated to anticipating and exceeding customer needs. Backed by extensive manufacturing capabilities, Thales works closely with customers and local industries to solve complex challenges for every operational environment.


PLEASE VISIT

Thales Group

Download HD photos


 


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Contacts

PRESS


Thales, Media Relations

Thales Defense & Security, Inc.

Paul D. Mehney

+1 (240) 957-1387

Paul.mehney@thalesdsi.com


Thales, Media Relations

North America

Jennifer Tumminio

jennifer.tumminio@thalesgroup.com


 

Elliptic Intelligence Used by the FBI in Action Against Huione, the $134 Billion Criminal Marketplace and Money Laundering Operation

 WASHINGTON - Wednesday, 24. June 2026 AETOSWire  


 


(BUSINESS WIRE)--Elliptic, the global leader in digital asset decisioning, today announced that its intelligence was used by the Federal Bureau of Investigation in today's action against the operators of Huione Group. The Justice Department announced the seizure of a cloud computing account used by subsidiaries of the Huione Group, a Cambodia-based corporate conglomerate.


First exposed by Elliptic in July 2024, Huione Guarantee was a Telegram-based marketplace serving online fraudsters across Southeast Asia. Merchants sold money laundering services, stolen personal data, websites and other goods and services necessary to perpetrate so-called “pig-butchering” scams and other online fraud., By the time Huione was forced offline, it had received more than $31 billion in cryptoasset transactions, making it the largest illicit online marketplace ever recorded, more than 25 times larger than Silk Road and AlphaBay combined.


Huione Group’s payments arm, Huione Pay, was also implicated in the laundering of proceeds of online scams. Huione Pay received at least $103 billion in cryptoasset payments over its lifetime and ran physical outlets across Cambodia.


This FBI action is the latest in a series of enforcement outcomes against online scam infrastructure and Chinese money laundering organizations built on Elliptic's intelligence, which also contributed to Telegram's shutdown of Huione Guarantee in May 2025, the US Treasury's FinCEN designation of Huione Group as a primary money laundering concern, and UK sanctions against Xinbi.


Simone Maini, CEO of Elliptic, said: "Huione was the largest illicit marketplace the world has ever seen. Elliptic’s data made the marketplace visible. Tracing the vast network behind it took years of intelligence work. This moment shows what the public and private sectors can achieve when they work together. These networks will keep adapting, and so will we."


About Elliptic


Elliptic is the leader in digital asset decisioning, we have built the most comprehensive platform for efficiently extracting cryptoasset data and intelligence across blockchains with the greatest accuracy.


Our platform’s unrivalled uptime, scalability, depth and breadth of our data and intelligence means exacting organizations choose Elliptic for their compliance, risk management, intelligence operations and blockchain infrastructure needs.


Founded in 2013, Elliptic is headquartered in London with offices in New York, Washington D.C., Miami, Dubai, Hong Kong, Singapore and Tokyo. To learn more, visit www.elliptic.co and follow us on LinkedIn and X.


 


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Rachel Matthews

Global Marketing and Communications Director, Elliptic

rachel.matthews@elliptic.co

Quectel Introduces NXP-based FCM365X Wi-Fi 6, Bluetooth LE 5.4, Zigbee and Thread Module for Smart Home and Industrial IoT Solutions

 


BELGRADE, Serbia - 

(BUSINESS WIRE) -- Quectel Wireless Solutions, a global end-to-end IoT solutions provider, today announces the launch of the FCM365X, a dual band Wi-Fi 6 and Bluetooth Low Energy (BLE) 5.4 module that is based on the NXP® Semiconductors RW612 wireless MCU and supports multiple protocols, including Zigbee and Thread. The module is powered by a high-performance Arm® Cortex®-M33 processor with TrustZone® technology, operating at up to 260MHz. It integrates 1.2MB of SRAM and 8MB of Flash memory, with optional PSRAM expansion available, delivering the performance and memory capacity required for demanding IoT applications.


As smart home and industrial IoT ecosystems continue to evolve, support for interoperable standards such as Thread and Zigbee is becoming increasingly important. These protocols enable low-power, reliable mesh networking that allows devices to communicate across diverse ecosystems. Thread is gaining momentum as a key technology for Matter-enabled devices, while Zigbee continues to see widespread adoption in smart home and building automation applications. By integrating Wi-Fi, Bluetooth LE, Zigbee and Thread into a single module, the FCM365X provides developers with the flexibility to address multiple connectivity requirements while simplifying device design and supporting future-ready applications.


“A broad range of use cases across smart homes and industrial IoT are increasingly looking for compact, low power devices that offer secure, short-range connectivity,” commented Lazaros Kapsias, EMEA Product Manager, Quectel Wireless Solutions. “We see the FCM365X helping to meet these needs in the smart home ecosystem and in industrial scenarios. The wide range of supported interfaces, compliance with security standards and the compact form factor makes this module stand out.”


Ideal for power constrained use cases such as smart home and industrial IoT devices, the module features several low power consumption modes and keep-alive mechanisms to provide flexibility and versatility. The FCM365X also supports GPIO, SDIO, UART, USB and JTAG interfaces as standard with I2C, I2S, ADC, LCD and PWM interfaces supported in the QuecOpen solution. In addition, the module complies with WPA-PSK, WPA2-PSK and WPA3-SAE security standards, supporting the AES-128 encryption algorithm.


Supporting both the 2.4GHz and 5GHz Wi-Fi bands via a 1x1 antenna, the FCM365X features an RF coaxial connector and offers a PCB antenna as an option. Weighing just 1.51g and with dimensions of 25.5mm x 18.0mm x 3.16mm, the module is compact and ideal for optimizing the size and cost of end products while offering maximized design flexibility. Robustness is assured with the module operating in the -40 °C to +85 °C temperature range.


About Quectel


Quectel’s passion for a smarter world drives us to accelerate IoT innovation. A highly customer-centric organization, we are a global end-to-end IoT solutions provider backed by outstanding support and services.


With a worldwide team of over 5,800 professionals, we lead the way in delivering end-to-end IoT solutions, spanning cellular, GNSS, satellite, Wi-Fi and Bluetooth modules, high-performance antennas, value-added services and full turnkey offerings including ODM services and system integration.


With regional offices and support across the globe, our international leadership is devoted to advancing IoT and helping build a smarter world.


For more information, please visit: www.quectel.com or LinkedIn


 


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MSCI Announces the Results of the MSCI 2026 Market Classification Review

 NEW YORK - 

(BUSINESS WIRE)--MSCI released the results of the MSCI 2026 Market Classification Review.


Key takeaways from this year's review include:


Reclassification of Bulgaria from Standalone to Frontier Market status

Assessment of shareholder transparency and coordinated trading concerns in the Indonesian and Turkish equity markets, acknowledging the announced steps undertaken by both markets to address these matters and noting the continued potential for future consultations on the appropriate treatment of these markets if credible progress is not observed

Acknowledgement of the removal of floor prices in Bangladesh, with a caution that any reintroduction could prompt a consultation on reclassification from Frontier to Standalone Market status

Ongoing monitoring of the implementation of measures aimed at improving the accessibility of the Korean equity market for international institutional investors

Reminder on the reclassification of Greece from Emerging to Developed Market status at the May 2027 Index Review

“The MSCI Market Classification Framework determines whether a market is developed, emerging, or frontier based on the accessibility and investability that international institutional investors actually experience,” said Raman Aylur Subramanian, Head of Market Classification and Taxonomies. “Index inclusion and market classification are not static judgments. They must be continuously assessed against market changes and the experience of international institutional investors. When market access or experiences worsen, our framework requires us to respond decisively. And when market accessibility and investability improve in a meaningful and sustained way, markets can progress through the classification framework, as seen with Bulgaria and Greece.”


More information related to the MSCI 2026 Market Classification Review, including the results of the 2026 MSCI Global Market Accessibility Review, can be viewed at: www.msci.com/market-classification.


Results of the Consultation on the Classification of Bulgaria


MSCI announced its decision to reclassify Bulgaria from Standalone Market status to Frontier Market status. The reclassification proposal was originally launched for consultation in 2024, after enough Bulgarian securities met the Size and Liquidity Requirements for Frontier Markets. The decision was subsequently deferred following feedback from international institutional investors, who cited limited market liquidity and the timing of the euro adoption.


Since then, conditions have materially improved. Market participants agreed that liquidity on the Bulgarian Stock Exchange (BSE) has improved meaningfully, supported by a higher number of securities meeting the Frontier Market Size and Liquidity Requirements and rising turnover. No significant operational challenges were identified following Bulgaria's transition to the euro, which was completed on January 1, 2026, when BSE's trading and post-trading infrastructure transitioned fully to euro denomination. Bulgaria had previously migrated to the European Central Bank's TARGET2-Securities (T2S) platform in September 2023, and following euro adoption, all settlements now occur in euros.


The reclassification will be implemented in one step across all standard, custom and derived MSCI Indexes, coinciding with the May 2027 Index Review. MSCI will share additional details on the implementation process in due course.


The accessibility report for Bulgaria is now reflected in the MSCI 2026 Global Market Accessibility Review report available at https://www.msci.com/market-classification.


Shareholder Transparency and Coordinated Trading Concerns


International institutional investors frequently raise concerns with MSCI when they experience persistent opacity in shareholding structures and suspect coordinated trading behavior. Both concerns materially limit investors' ability to assess true free float and to rely on observed market prices for portfolio construction and index replication, and they relate directly to the Information Flow and Market Infrastructure pillars of the MSCI Market Accessibility framework.


For Indonesia, market participants raised profound investability concerns stemming from these issues. MSCI acknowledges the recent transparency reforms announced by Otoritas Jasa Keuangan (OJK), PT Bursa Efek Indonesia (IDX), and PT Kustodian Sentral Efek Indonesia (KSEI), including enhanced disclosure of shareholders with ownership above 1%, more granular investor classification, the introduction of a High Shareholding Concentration (HSC) framework, and a roadmap to raise the minimum free float requirement to 15%. While these announcements represent a step in the right direction, what matters for international institutional investors is the consistent implementation and sustained effect of these measures across the market. MSCI will continue to assess their scope, consistency and sustained effectiveness in the context of free float determination and broader investability assessments. Should sufficient progress not be evident by the time of the November 2026 MSCI Index Review, MSCI will consider a range of options for the appropriate treatment for the Indonesia market, potentially including a consultation on the reclassification of Indonesia from Emerging Markets to Frontier Markets.


For Turkey, international institutional investors have highlighted recurring instances of possible coordinated trading behavior involving fund holdings closely affiliated with certain smaller, listed companies, with the effect of artificially inflating free float estimates. MSCI acknowledges the decision issued by the Capital Markets Board of Turkey (SPK), which recently introduced a framework for excluding fund-held stakes from the exchange’s free float calculations where the underlying beneficial ownership belongs to parties already excluded from free float. Nevertheless, market participants want to see the impact of these adjusted calculations in practice. Additionally, international investors have communicated that they seek further progress, including granular and timely disclosure of beneficial ownership, robust surveillance and enforcement against coordinated trading behavior, and a transparent, rules-based framework for the identification and treatment of securities exhibiting structurally distorted free float. If sufficient tangible and credible progress is not evident in the Turkey market by the time of the November 2026 MSCI Index Review, MSCI may launch a consultation on the appropriate treatment for Turkey and its eligible securities.


MSCI continues to welcome feedback on shareholder transparency and trading behavior in these markets.


Removal of Floor Prices in Bangladesh


Floor prices have now been removed from all affected securities in the Bangladesh equity market. MSCI welcomes this development. Floor prices severely hinder a market's accessibility, distorting price discovery and impairing the ability of international institutional investors to enter and exit positions at fair value, and their removal is an important step toward restoring the investability of the market.


MSCI cautions that the reintroduction of floor prices on any listed securities would once again severely impair the accessibility of the Bangladesh equity market. Should floor prices be reimposed, MSCI may launch a consultation on a potential reclassification of Bangladesh from Frontier Market status to Standalone Market status. MSCI continues to welcome feedback on the accessibility of the Bangladesh equity market.


Market Accessibility of Korea


From 2008 to 2014, MSCI consulted with global market participants on the potential reclassification of Korea from Emerging Market status to Developed Market status. Market participants identified the limited convertibility of the Korean won in the offshore currency market as a key barrier to reclassification. Other accessibility issues highlighted at the time included the rigidity of the investor ID system, the restrictions on in-kind transfers and off-exchange transactions, and the limited availability of investment instruments stemming from restrictions on the use of exchange data for the creation of financial products.


MSCI acknowledges the measures announced by Korean market authorities to address these long-standing concerns. However, investors have communicated that the underlying issues have not been fully resolved. The Korean won is not deliverable offshore. Even more concerning, onshore liquidity during the extended FX trading hours remains largely insufficient to support tight execution at standards comparable to those observed in developed markets, constraining FX operational flexibility for index replicators and others. International institutional investors will need to be convinced that this trading of the won in overnight markets in Korea will eventually provide large, deep and consistent pools of liquidity and tight bid/ask spreads that are comparable to day trading hours for other developed market currencies in the world. Operational adoption of omnibus accounts and in-kind transfers remains limited. Following the lifting of the short-selling ban, market participants continue to face significant operational burdens under the reinstated compliance regime. In addition, early pre-settlement funding requirements remain a burden for market participants.


MSCI will continue to monitor implementation and engage with market participants and Korean authorities. As a reminder, potential reclassification consultations require that all issues have been addressed, reforms have been fully implemented, and market participants have had ample time to thoroughly evaluate the sustained effectiveness of the changes.


Market Classification of Greece


On March 31, 2026, MSCI announced its decision to reclassify Greece from Emerging Market status to Developed Market status, following a consultation launched on January 26, 2026. The majority of consultation participants favored the proposed reclassification, recognizing that Greece's market infrastructure has converged with Developed European standards and meets the criteria for MSCI Developed Markets.


The reclassification will be implemented in one step across all standard, custom and derived MSCI Indexes, coinciding with the May 2027 Index Review. Once reclassified, Greece will be incorporated into the Developed Europe single market index construction process, and existing constituent rules will be applied to minimize turnover at the time of the reclassification.


-Ends-


About MSCI


MSCI (NYSE: MSCI Inc.) strengthens global markets by connecting participants across the financial ecosystem with a common language. Our research-based data, analytics and indexes, supported by advanced technology, set standards for global investors and help our clients understand risks and opportunities so they can make better decisions and unlock innovation. We serve asset managers and owners, private-market sponsors and investors, hedge funds, wealth managers, banks, insurers and corporates. To learn more, please visit www.msci.com.


The process for submitting a formal index complaint can be found on the index regulation page of MSCI’s website at: https://www.msci.com/index-regulation.


 

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Media Inquiries

PR@msci.com

Melanie Blanco +1 212 981 1049

Konstantinos Makrygiannis +44 77 6893 0056

Tina Tan +852 2844 9320


MSCI Global Client Service

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New Pivotal Study Data Show Takeda’s Oveporexton Improved Daily Function, Cognition and Nighttime Sleep for People with Narcolepsy Type 1

 - Secondary and Exploratory Endpoint Results from Phase 3 Studies Presented at SLEEP 2026 Underscore Improvements with Oveporexton Across a Broad Range of Daytime and Nighttime Symptoms

- Takeda is on Track to Bring the First and Only Orexin Agonist to People Living with Narcolepsy Type 1 with Regulatory Submissions Under Review


 


(BUSINESS WIRE)--Takeda (TSE:4502/NYSE:TAK) today presented additional results from two pivotal studies at SLEEP 2026, showing oveporexton (TAK-861), an oral orexin receptor 2 (OX2R)-selective agonist, improved daily functioning as well as cognitive and sleep-related symptoms associated with narcolepsy type 1 (NT1).1,2,3 Oveporexton is designed to address the underlying orexin deficiency that causes NT1 by restoring orexin signaling. These data, along with previously disclosed Phase 3 results, demonstrated improvement across the broad disease spectrum, supporting the potential of oveporexton to redefine the standard of care for NT1.4


"Narcolepsy type 1 is a 24-hour disease driven by orexin deficiency, and while excessive daytime sleepiness and cataplexy are the most recognized symptoms, many people experience additional bothersome symptoms such as cognitive difficulties and disrupted nighttime sleep," said Emmanuel Mignot, M.D., Ph.D., principal investigator for the FirstLight (TAK-861-3001) Phase 3 study. "Oveporexton has demonstrated significant improvement across a broad range of NT1 symptoms, daily functioning and quality of life with the potential to shift disease management beyond incremental symptom relief.”


The presentations highlighted results from secondary and exploratory endpoints from two global, multicenter, placebo-controlled studies—FirstLight (TAK-861-3001; twice-daily 2mg, 1mg and placebo) and RadiantLight (TAK-861-3002; twice-daily 2mg and placebo)—including:


Functioning: At all doses, oveporexton significantly improved daily functioning at week 12 compared to placebo (p<0.001) across the six domains of the Functional Impacts of Narcolepsy Instrument (FINI). Most patients reached or exceeded the published normative domain thresholds, underscoring oveporexton’s ability to allow individuals to manage their everyday lives.5 FINI reflects the domains that are of highest impact for NT1 including tiredness, cognitive functioning, cataplexy, social activities, everyday activities and everyday responsibilities.

Cognition: Oveporexton improved cognitive symptoms associated with NT1 compared to placebo, as measured using objective neuropsychological tests of attention, executive function and memory along with patient-reported measures. On the FINI Cognitive Function domain, approximately 70% of patients across all doses reported no significant cognitive difficulties compared to approximately 15% of patients in the placebo arm.

Nighttime Sleep: Exploratory endpoints demonstrated that oveporexton improved quality of sleep across both studies. Across all doses, most patients reported no hallucinations or sleep paralysis and most patients on the 2/2mg dose reported meaningful reductions in disturbed nighttime sleep from baseline. Additionally, the timing and pattern of rapid eye movement (REM) sleep shifted toward those seen in healthy controls.

"Narcolepsy type 1 is not defined by a single symptom, which is why we designed a comprehensive Phase 3 program to evaluate the effect of oveporexton on the broad disease impact,” said Sarah Sheikh, M.Sc., B.M., B.Ch., MRCP, Head, Neuroscience Therapeutic Area Unit and Global Development at Takeda. “We are grateful to the patients, caregivers and healthcare providers who have been a part of this journey. With oveporexton under review by multiple regulatory agencies, we are on the cusp of bringing the first and only orexin agonist to the narcolepsy type 1 community, with the potential to redefine the standard of care if approved.”


Takeda will present additional data at the conference, including pooled analyses from previously presented Phase 3 results, data evaluating the impact of oveporexton in reducing microsleeps and an evaluation of the holistic symptom impact of NT1 in the United States.


About Oveporexton (TAK-861)


Oveporexton (TAK-861) is an investigational orexin receptor 2 (OX2R)-selective agonist, which selectively stimulates the OX2R to restore signaling and address the underlying orexin deficiency that causes narcolepsy type 1 (NT1). By activating OX2Rs, oveporexton is designed to promote wakefulness and reduce abnormal rapid eye movement (REM)-sleep like phenomena, including cataplexy, to address a broad spectrum of daytime and nighttime symptoms. The United States Food and Drug Administration (FDA) accepted the New Drug Application (NDA) and granted Priority Review for oveporexton, with a Prescription Drug User Fee Act (PDUFA) goal date in the third quarter of this calendar year. Regulatory submissions for oveporexton are also under review in China and Japan, with additional submissions planned throughout the year. Oveporexton is an investigational compound that has not been approved for use by any regulatory authority.


About the FirstLight and RadiantLight Phase 3 Orexin Studies


FirstLight (TAK-861-3001; NCT06470828) and RadiantLight (TAK-861-3002; NCT06505031) are global, multicenter, placebo-controlled studies to evaluate the efficacy, safety and tolerability of oveporexton compared to placebo in patients with narcolepsy type 1 (NT1) over 12 weeks. The studies were conducted in 19 countries, with enrollment completed within six months. The FirstLight study enrolled 168 participants randomized to one of three dosing arms (twice-daily 2mg, 1mg and placebo). The RadiantLight study enrolled 105 participants randomized to two dosing arms (twice-daily 2mg and placebo). More than 95 percent of the participants who completed the studies enrolled in the ongoing long-term extension (LTE) study.


About Takeda


Takeda is focused on creating better health for people and a brighter future for the world. We aim to discover and deliver life-transforming treatments in our core therapeutic and business areas, including gastrointestinal and inflammation, rare diseases, plasma-derived therapies, oncology, neuroscience and vaccines. Together with our partners, we aim to improve the patient experience and advance a new frontier of treatment options through our dynamic and diverse pipeline. As a leading values-based, R&D-driven biopharmaceutical company headquartered in Japan, we are guided by our commitment to patients, our people and the planet. Our employees in approximately 80 countries and regions are driven by our purpose and are grounded in the values that have defined us for more than two centuries. For more information, visit www.takeda.com.


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References


1 Plazzi G, Dauvilliers Y, Pizza F, et al. Effect of the Oral Orexin Receptor 2 Agonist Oveporexton (TAK-861) on Functional Impacts of Narcolepsy Type 1: Results from Two Phase 3 Studies. Presented at: SLEEP 2026; 14-17 June 2026; Baltimore, MD.

2 Pizza F, Dauvilliers Y, Del Rio Villegas R, et al. Oveporexton (TAK-861) Improves Cognitive Symptoms in Patients with Narcolepsy Type 1: Results from Two Randomized, Placebo-controlled Phase 3 Trials. Presented at: SLEEP 2026; 14-17 June 2026; Baltimore, MD.

3 Barateau L, Gong Y, Dauvilliers Y, et al. Effects of Treatment with Oveporexton, an Orexin Receptor 2 Agonist, on Sleep in People with Narcolepsy Type 1: Phase 3 Results. Presented at: SLEEP 2026; 14-17 June 2026; Baltimore, MD.

4 The topline results of these studies were shared on September 8, 2025, in “Takeda Presents Orexin Data from Landmark Oveporexton (TAK-861) Phase 3 Program in Narcolepsy Type 1 at World Sleep 2025.”

5 Crawford S, et al. Sleep 2024;47(suppl 1):A288.


 


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